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InVivo BioTech Services t84.1
B cell aggregation was induced by 16 h of incubation with anti-CD19 ( A , compare untreated to anti-CD19-treated cells). ( B – D ) Inhibition of CD19-induced B cell aggregation by the anti-CEACAM1 antibody clones C5-1X (150 μg/ml) ( B ), 4D1/C2 (150 μg/ml) ( C ) and <t>T84.1</t> (150, 250 vs . 400 μg/ml) ( D ). B cells were isolated from n = 3 ( B,C ) or n = 9 ( D ) healthy donors, respectively. ( E ) Induction of B cell aggreation by anti-CD19 antibody and its inhibition by T84.1 in age- and gender-matched MS patients ( n = 4) and healthy controls ( n = 4).
T84.1, supplied by InVivo BioTech Services, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/t84%2E1/pmc04951702-241-11-12?v=InVivo+BioTech+Services
Average 90 stars, based on 1 article reviews
t84.1 - by Bioz Stars, 2026-07
90/100 stars

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1) Product Images from "CEACAM1 mediates B cell aggregation in central nervous system autoimmunity"

Article Title: CEACAM1 mediates B cell aggregation in central nervous system autoimmunity

Journal: Scientific Reports

doi: 10.1038/srep29847

B cell aggregation was induced by 16 h of incubation with anti-CD19 ( A , compare untreated to anti-CD19-treated cells). ( B – D ) Inhibition of CD19-induced B cell aggregation by the anti-CEACAM1 antibody clones C5-1X (150 μg/ml) ( B ), 4D1/C2 (150 μg/ml) ( C ) and T84.1 (150, 250 vs . 400 μg/ml) ( D ). B cells were isolated from n = 3 ( B,C ) or n = 9 ( D ) healthy donors, respectively. ( E ) Induction of B cell aggreation by anti-CD19 antibody and its inhibition by T84.1 in age- and gender-matched MS patients ( n = 4) and healthy controls ( n = 4).
Figure Legend Snippet: B cell aggregation was induced by 16 h of incubation with anti-CD19 ( A , compare untreated to anti-CD19-treated cells). ( B – D ) Inhibition of CD19-induced B cell aggregation by the anti-CEACAM1 antibody clones C5-1X (150 μg/ml) ( B ), 4D1/C2 (150 μg/ml) ( C ) and T84.1 (150, 250 vs . 400 μg/ml) ( D ). B cells were isolated from n = 3 ( B,C ) or n = 9 ( D ) healthy donors, respectively. ( E ) Induction of B cell aggreation by anti-CD19 antibody and its inhibition by T84.1 in age- and gender-matched MS patients ( n = 4) and healthy controls ( n = 4).

Techniques Used: Incubation, Inhibition, Clone Assay, Isolation



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B cell aggregation was induced by 16 h of incubation with anti-CD19 ( A , compare untreated to anti-CD19-treated cells). ( B – D ) Inhibition of CD19-induced B cell aggregation by the anti-CEACAM1 antibody clones C5-1X (150 μg/ml) ( B ), 4D1/C2 (150 μg/ml) ( C ) and <t>T84.1</t> (150, 250 vs . 400 μg/ml) ( D ). B cells were isolated from n = 3 ( B,C ) or n = 9 ( D ) healthy donors, respectively. ( E ) Induction of B cell aggreation by anti-CD19 antibody and its inhibition by T84.1 in age- and gender-matched MS patients ( n = 4) and healthy controls ( n = 4).
T84.1, supplied by InVivo BioTech Services, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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B cell aggregation was induced by 16 h of incubation with anti-CD19 ( A , compare untreated to anti-CD19-treated cells). ( B – D ) Inhibition of CD19-induced B cell aggregation by the anti-CEACAM1 antibody clones C5-1X (150 μg/ml) ( B ), 4D1/C2 (150 μg/ml) ( C ) and <t>T84.1</t> (150, 250 vs . 400 μg/ml) ( D ). B cells were isolated from n = 3 ( B,C ) or n = 9 ( D ) healthy donors, respectively. ( E ) Induction of B cell aggreation by anti-CD19 antibody and its inhibition by T84.1 in age- and gender-matched MS patients ( n = 4) and healthy controls ( n = 4).
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B cell aggregation was induced by 16 h of incubation with anti-CD19 ( A , compare untreated to anti-CD19-treated cells). ( B – D ) Inhibition of CD19-induced B cell aggregation by the anti-CEACAM1 antibody clones C5-1X (150 μg/ml) ( B ), 4D1/C2 (150 μg/ml) ( C ) and <t>T84.1</t> (150, 250 vs . 400 μg/ml) ( D ). B cells were isolated from n = 3 ( B,C ) or n = 9 ( D ) healthy donors, respectively. ( E ) Induction of B cell aggreation by anti-CD19 antibody and its inhibition by T84.1 in age- and gender-matched MS patients ( n = 4) and healthy controls ( n = 4).
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B cell aggregation was induced by 16 h of incubation with anti-CD19 ( A , compare untreated to anti-CD19-treated cells). ( B – D ) Inhibition of CD19-induced B cell aggregation by the anti-CEACAM1 antibody clones C5-1X (150 μg/ml) ( B ), 4D1/C2 (150 μg/ml) ( C ) and <t>T84.1</t> (150, 250 vs . 400 μg/ml) ( D ). B cells were isolated from n = 3 ( B,C ) or n = 9 ( D ) healthy donors, respectively. ( E ) Induction of B cell aggreation by anti-CD19 antibody and its inhibition by T84.1 in age- and gender-matched MS patients ( n = 4) and healthy controls ( n = 4).
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Thermo Fisher alexa-546 conjugated mab t84.1
B cell aggregation was induced by 16 h of incubation with anti-CD19 ( A , compare untreated to anti-CD19-treated cells). ( B – D ) Inhibition of CD19-induced B cell aggregation by the anti-CEACAM1 antibody clones C5-1X (150 μg/ml) ( B ), 4D1/C2 (150 μg/ml) ( C ) and <t>T84.1</t> (150, 250 vs . 400 μg/ml) ( D ). B cells were isolated from n = 3 ( B,C ) or n = 9 ( D ) healthy donors, respectively. ( E ) Induction of B cell aggreation by anti-CD19 antibody and its inhibition by T84.1 in age- and gender-matched MS patients ( n = 4) and healthy controls ( n = 4).
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B cell aggregation was induced by 16 h of incubation with anti-CD19 ( A , compare untreated to anti-CD19-treated cells). ( B – D ) Inhibition of CD19-induced B cell aggregation by the anti-CEACAM1 antibody clones C5-1X (150 μg/ml) ( B ), 4D1/C2 (150 μg/ml) ( C ) and T84.1 (150, 250 vs . 400 μg/ml) ( D ). B cells were isolated from n = 3 ( B,C ) or n = 9 ( D ) healthy donors, respectively. ( E ) Induction of B cell aggreation by anti-CD19 antibody and its inhibition by T84.1 in age- and gender-matched MS patients ( n = 4) and healthy controls ( n = 4).

Journal: Scientific Reports

Article Title: CEACAM1 mediates B cell aggregation in central nervous system autoimmunity

doi: 10.1038/srep29847

Figure Lengend Snippet: B cell aggregation was induced by 16 h of incubation with anti-CD19 ( A , compare untreated to anti-CD19-treated cells). ( B – D ) Inhibition of CD19-induced B cell aggregation by the anti-CEACAM1 antibody clones C5-1X (150 μg/ml) ( B ), 4D1/C2 (150 μg/ml) ( C ) and T84.1 (150, 250 vs . 400 μg/ml) ( D ). B cells were isolated from n = 3 ( B,C ) or n = 9 ( D ) healthy donors, respectively. ( E ) Induction of B cell aggreation by anti-CD19 antibody and its inhibition by T84.1 in age- and gender-matched MS patients ( n = 4) and healthy controls ( n = 4).

Article Snippet: The three clones C5-1X (Reliatech), 4D1/C2 (produced and purified in-house) and T84.1 (inVivo BioTech Services) were tested at different concentrations (150 μg/ml, 250 μg/ml and 400 μg/ml).

Techniques: Incubation, Inhibition, Clone Assay, Isolation